Multiple sclerosis

Multiple sclerosis is the most common cause of chronic neurologic disability in young adults.1  Its prevalence varies geographically, and is as common as 2.5 per 1000 in certain areas.1 The exact cause of multiple sclerosis is uncertain but what is known is that the patient’s own antibodies mistakenly direct their “attack” against the body’s nerve cells.2  It is a complex disorder that is characterized by injury to a part of the nerve called the axon.  The damage results in inflammation, which along with the initial insult, results in delayed conduction and communication between nerves. Over time, the patient develops fatigue, weakness, numbness, pain, loss of vision, other health problems.3  Tools available to diagnosis multiple sclerosis include MRI or evaluation of the cerebrospinal fluid.

Integrative therapies to address multiple sclerosis include smoking-cessation, exercise, exposure to sunshine, mindful meditation.4,5,6  Dietary factors influence the course of multiple sclerosis via modulation of inflammation.7  Eating a diet relatively high in omega-3, polyunsaturated fatty acids is associated with positive health effects. Primary sources of such foods include cold water fish, nuts, seeds, and dark green leafy vegetables which have been shown to reduce inflammation.8  Patients with active symptoms may also benefit from the effects of a structured elimination diet. This involves elimination of common or suspected food allergens or triggers for at least 2-4 weeks followed by a systematic rechallenge.9

Supplementing one’s diet with vitamin D10, alpha-lipoic acid, N-acetylcysteine, glutathione11, and B complex vitamins12 have been shown to reduce disease severity.  Intravenous ozone therapy is another powerful anti-inflammatory tool used to reduce symptoms due to inflammation.  In addition, botanicals such as curcumin13 and ginkgo biloba 14 have demonstrated some potential in being able to address symptoms of multiple sclerosis. Testosterone has been shown to exhibit neuroprotective effects, thus ameliorating multiple sclerosis symptoms in men with active disease.15  At Rocky Mountain Regenerative Medicine, we have the knowledge and ability to administer these supplements intravenously, at the appropriate dose to help manage symptoms.


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  2. E.M. Frohman, M. Filippi, O. Stuve, et al.: Characterizing the mechanisms of progression in multiple sclerosis. Arch Neurol. 62:1345-1356 2005
  3. B. Weinstock-Guttman, L.D. Jacobs: What is new in the treatment of multiple sclerosis?. Drugs. 59:401-410 2000
  4. A. Andreasen, E. Stenager, U. Dalgas: Mult Scler: the effect of exercise therapy on fatigue in multiple sclerosis. 17 (9):1041-1054 2011
  5. D.M. Freedman, M. Dosemeci, M.C. Alavanja: Mortality from multiple sclerosis and exposure to residential and occupational solar radiation: a case-control study based on death certificates. Occup Environ Med. 57:418-421 2000
  6. P. Grossman, L. Kappos, H. Gensicke, et al.: MS quality of life, depression, and fatigue improve after mindfulness training: a randomized trial. Neurology. 75:1141-1149 2010
  7. P. Riccio, R. Rossano: Nutrition facts in multiple sclerosis. ASN Neuro. 18; 7 (1)2015 Feb
  8. M. Mayer: Essential fatty acids and related molecular and cellular mechanisms in multiple sclerosis: new looks at old concepts. Folia Biol (Praha). 45:133-141 1999
  9. S. Jacob, M. Zarei, A. Kenton, H. Allroggen: Gluten sensitivity and neuromyelitis optica: two case reports. J Neurol Neurosurg Psychiatry. 76:1028-1030 2005
  10. K.L. Munger, S.M. Zhang, E. O’Reilly, M.A. Hernan, M.J. Olek, W.C. Willett, et al.: Vitamin D intake and incidence of multiple sclerosis. Neurology. 62:60-65 2004
  11. M.E. van Meeteren, et al.: Antioxidants and polyunsaturated fatty acids in multiple sclerosis. European Journal of Clinical Nutrition. 59:1347-1361 2005
  12. J. Kira, S. Tobimatsu, I. Goto: Vitamin B12 metabolism and massive dose methyl vitamin B12 therapy in Japanese patients with multiple sclerosis. Intern Med. 33:82-861994
  13. NCT01514370. URL: Accessed Dec 01 2015
  14. J.R. Plemel, et al.: Over-the-counter anti-oxidant therapies for use in multiple sclerosis. A systematic review. Mult Sclerosis J. Vol 21 (12):1485-1495 2015
  15. S.M. Gold, et al.: Estrogen and testosterone therapies in multiple sclerosis. Prog Brain Res. 175:239-251 2009