Prospective Safety and Efficacy Study for the Use of Adipose Derived Cellular Therapy in Degenerative Lumbar Spine Disorders. Written by Vassily Eliopoulos and published by the International Journal of Stem Cell Research & Therapy, Volume 9, Issue 1.
ABSTRACT
Introduction: Low back pain is a significant cause of disability worldwide. This study looks at the safety and efficacy of Autologous Adipose Derived Cellular Therapy in the form of Stromal Vascular Fraction (SVF) as a minimally invasive treatment option for low back pain.
Methods: This is a prospective, patient funded, IRB approved study looking at 549 patients who suffered from low back pain related to degenerative spinal conditions. The patients underwent SVF harvesting and deployment using a standard protocol. Data was collected using an online, automated database process.
Results: With a single SVF intervention significant pain improvement was documented out to 2 years from the time of intervention (79% of respondents reported significant pain improvement at 24 months). Adverse events were minimal and in line with or better than traditional minimally invasive therapies. No significant morbidity or mortality was identified.
Discussion: SVF appears to be a safe and effective therapy for low back pain caused by degenerative Lumbar Spine conditions.
